In the context of "Left Behind" and its extended universe, paganism is used as a catch-all term for religious beliefs that are polytheistic and either do not include Yahweh, or consider Him one of the Gods rather than the only God.
In "Kingdom Come", Cendrillon Jospin expresses wistfulness about "wishing she had Pagan parents" to her friend Bahira Ababneh.
In "Left Beyond Quest", Paganism is occasionally shown to have resurfaced, due to environmental or social factors that encourage it. The Omega even attempts to foster Pagan beliefs in a bid to study the effectiveness of non-Christian religion when it comes to having prayers answered; its results are inconclusive.